Noni juice is a tropical drink derived from the fruit of the Morinda citrifolia tree.

This tree and its fruit grow among lava flows in Southeast Asia, especially in Polynesia.

Noni (pronounced NO-nee) is a lumpy, mango-sized fruit that is yellow in color. It’s very bitter and has a distinct odor that is sometimes compared to stinky cheese.

Polynesian peoples have used noni in traditional folk medicine for over 2,000 years. It’s commonly used to treat health issues like constipation, infections, pain, and arthritis

Today, noni is mostly consumed as a juice blend. The juice is packed with potent antioxidants and may provide several health benefits.

This article provides everything you need to know about noni juice, including its nutrients, potential health benefits, and safety.

The nutritional content of noni juice varies widely.

One study analyzed 177 different brands of noni juice and found significant nutritional variability among them

This is because noni juice is often mixed with other fruit juices or added sweeteners to mask its bitter taste and foul odor.

That said, Tahitian Noni Juice — produced by Morinda, Inc. — is the most popular brand on the market and widely used in studies. It’s comprised of 89% noni fruit and 11% grape and blueberry juice concentrates

The nutrients in 3.5 ounces (100 ml) of Tahitian Noni Juice are

• Calories: 47 calories
• Carbs: 11 grams
• Protein: less than 1 gram
• Fat: less than 1 gram
• Sugar: 8 grams
• Vitamin C: 33% of the Reference Daily Intake (RDI)
• Biotin: 17% of the RDI
• Folate: 6% of the RDI
• Magnesium: 4% of the RDI
• Potassium: 3% of the RDI
• Calcium: 3% of the RDI
• Vitamin E: 3% of the RDI

Like most fruit juice, noni juice contains mostly carbs. It’s rich in vitamin C, which is essential for skin and immune health

Additionally, it’s a great source of biotin and folate — B vitamins that play many important roles in your body, including helping convert food into energy

Noni juice is known for its high levels of antioxidants.

Antioxidants prevent cellular damage caused by molecules called free radicals. Your body requires a healthy balance of antioxidants and free radicals to maintain optimal health

Researchers suspect that the potential health benefits of noni juice are likely related to its powerful antioxidant properties

The main antioxidants in noni juice include beta carotene, iridoids, and vitamins C and E

In particular, Iridoids demonstrate strong antioxidant activity in test-tube studies — although more research is needed to confirm their effects in humans

Nonetheless, studies indicate that a diet rich in antioxidants — such as those found in noni juice — may lower your risk of chronic conditions like heart disease and diabetes

Noni juice has a number of potential benefits. Still, it’s important to keep in mind that research into this fruit is relatively recent — and more studies are needed on many of these health effects.

May reduce cellular damage from tobacco smoke

Noni juice may reduce cellular damage — particularly from tobacco smoke.

Exposure to tobacco smoke generates dangerous amounts of free radicals. Excessive amounts can cause cellular damage and lead to oxidative stress

Oxidative stress is associated with many ailments, including heart disease, diabetes, and cancer. Studies show that consuming foods rich in antioxidants may reduce oxidative stress

In one study, heavy tobacco smokers were given 4 ounces (118 ml) of noni juice per day. After 1 month, they experienced a 30% reduction of two common free radicals compared to their baseline levels .

Tobacco smoke is also known to cause cancer. Certain chemicals from tobacco smoke may bind to cells in your body and lead to tumor growth

Noni juice may reduce levels of these cancer-causing chemicals. Two clinical trials found that drinking 4 ounces (118 ml) of noni juice daily for 1 month reduced the levels of cancer-causing chemicals in tobacco smokers by about 45%

Yet, noni juice does not negate all of smoking’s negative health effects — and should not be considered a replacement for quitting.

May support heart health in smokers

Noni juice may support heart health by lowering cholesterol levels and reducing inflammation.

Cholesterol has many important functions in your body, but certain types in excess may increase your risk of heart disease — as may chronic inflammation

One study found that drinking up to 6.4 ounces (188 ml) of noni juice per day for 1 month significantly reduced total cholesterol, LDL (bad) cholesterol levels, and the inflammatory blood marker C-reactive protein

However, the subjects of the study were heavy cigarette smokers, so the results cannot be generalized to all people. Researchers suspect that noni juice’s antioxidants may reduce the high cholesterol levels caused by smoking tobacco

A separate, 30-day study gave non-smokers 2 ounces (59 ml) of noni juice twice daily. Participants did not experience significant changes in cholesterol levels.

These results suggest that the cholesterol-lowering effect of noni juice may only apply to heavy cigarette smokers.

That said, more research on noni juice and cholesterol is needed.

May improve endurance during exercise

Noni juice may improve physical endurance. In fact, Pacific Islanders believed that eating noni fruit strengthened the body during long fishing trips and voyages

A few studies show positive effects of drinking noni juice during exercise.

For example, one 3-week study gave long-distance runners 3.4 ounces (100 ml) of noni juice or a placebo twice daily. The group that drank noni juice experienced a 21% increase in average time to fatigue, which suggests improved endurance

Other human and animal research reports similar findings for using noni juice to combat fatigue and improve endurance

The increase in physical endurance associated with noni juice is likely related to its antioxidants — which may reduce the damage to muscle tissue that normally occurs during exercise

May relieve pain in people with arthritis

For over 2,000 years, noni fruit has been used in traditional folk medicine for its pain-relieving effects. Some research now supports this benefit.

For instance, in a 1-month study, people with degenerative arthritis of the spine took 0.5 ounces (15 ml) of noni juice twice daily. The noni juice group reported a significantly lower pain score — with complete relief of neck pain in 60% of participants

In a similar study, people with osteoarthritis took 3 ounces (89 ml) of noni juice daily. After 90 days, they experienced a significant decrease in the frequency and severity of arthritis pain, as well as an improved quality of life

Arthritis pain is often associated with increased inflammation and oxidative stress. Therefore, noni juice may provide natural pain relief by reducing inflammation and combatting free radicals

May improve immune health

Noni juice may support immune health.

Like some other fruit juices, it’s is rich in vitamin C. For example, 3.5 ounces (100 ml) of Tahitian Noni Juice packs about 33% of the RDI for this vitamin.

Vitamin C supports your immune system by protecting your cells from free radical damage and environmental toxins

Many other antioxidants present in noni juice — such as beta carotene — may improve immune health as well.

One small, 8-week study found that healthy people who drank 11 ounces (330 ml) of noni juice daily had increased immune cell activity and lower levels of oxidative stress.